The device allowed in vitro and in vivo activation of heat sensitive TRPV1 positive cells and nerve fibers in humans. First device that allows selective stimulation of Adelta and C fibers in Humans. The device is compatible with LEP/EEG and patch clamp recording. The device allow the best available homogeneous heating of skin and stimulation of small fibers regardless of depth of their location in the range 0-600 um.
